PROCESS FOR THE REDUCTIVE AMINATION OF ALDEHYDES AND KETONES VIA THE FORMATION OF MACROCYCLIC POLYIMINE INTERMEDIATES
摘要
Aldehyde or ketone compounds having more than one carbonyl group are reductively aminated to form a product amine compound having more than one primary amino group. The aldehyde or ketone compound is reacted with the product amine compound, to form a reaction mixture that contains one or more intermediates. The intermediate is then reductively aminated to form the desired product. This process produces the desired product in very high yields with low levels of secondary amine impurities.
申请公布号
WO2007005594(A2)
申请公布日期
2007.01.11
申请号
WO2006US25559
申请日期
2006.06.29
申请人
DOW GLOBAL TECHNOLOGIES, INC.;TULCHINSKY, MICHAEL, LEO;FISH, BARRY, B.