The invention relates to genetic elements capable of improving the levels of expression of operably-linked transcription units. In particular, said genetic elements are derived from the 5' untranslated regions of ribosomal protein genes and may comprise a CpG island. Also provided are vectors and host cells comprising said genetic elements and methods of use to obtain high levels of recombinant gene expression.
申请公布号
WO2006123097(A3)
申请公布日期
2007.01.11
申请号
WO2006GB01656
申请日期
2006.05.09
申请人
SEROLOGICALS INVESTMENT COMPANY INC.;SIMPSON, DAVID, JOHN;WILLIAMS, STEVEN, GERAINT;IRVINE, ALISTAIR, SIMPSON