| 摘要 |
A composition which comprises a solid or semi-solid matrix having at least o ne active ingredient uniformly dispersed therein, the matrix comprising at leas t one pharmaceutically acceptable matrix-forming agent and a 1,3-bis(lactamyl) - butane compound, in particular 1,3-bis(pyrrolidon-1-yl)-butane. The active ingredient is preferably dispersed in the matrix in a state of a solid solution. The matrix-forming agent is preferably a pharmaceutically acceptab le polymer. The composition is useful for the manufacture of pharmaceutical dosage forms. |
