发明名称 SUBSTITUTED 8'-PYRI(MI)DINYL-DIHYDROSPIRO-[CYCLOALKYLAMINE]-PYRIMIDO[1,2-a]PYRIMIDIN-6-ONE DERIVATIVES
摘要 The invention relates to a dihydrospiro-[cycloalkylamine]-pyrimidone derivative represented by formula (I) or a salt thereof: wherein X, Y, R1, R2, R3, R4, o, m, n, p and q are as defined herein. The invention relates also to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3beta, such as Alzheimer disease.
申请公布号 US2007010539(A1) 申请公布日期 2007.01.11
申请号 US20060423557 申请日期 2006.06.12
申请人 MITSUBISHI PHARMA CORPORATION 发明人 CHEREZE NATHALIE;LOCHEAD ALISTAIR;SAADY MOURAD;SLOWINSKI FRANCK;YAICHE PHILIPPE
分类号 A61K31/519;A61K31/505;C07D487/04;C07D487/14 主分类号 A61K31/519
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