Method for detecting diseases that are associated with defects of cystic fibrosis transmembrane conductance regulator (CFTR) protein

摘要

The invention concerns a method for the diagnosis of membrane channel defects in cells by comparing defective with non-defective cells with the following steps: influencing the volume regulation of the cells; recording the change of volume regulation resulting therefrom in non-defective cells; determining the existence of defective cells with a volume change deviating therefrom, in order to provide a suitable method which enables the identification of diseases based on CFTR defects, in particular cystic fibrosis, at an early stage.