发明名称 |
DIAGNOSTIC METHODS AND COMPOSITIONS RELATING TO THE PROTEOGLYCAN PROTEINS OF CARTILAGE BREAKDOWN |
摘要 |
This invention relates to methods and compositions for early diagnosis, monitoring and treatment of cartilage degenerative conditions including forms of arthritis and arthropathy, using an antibody which recognizes a peptide comprising the sequence FFGVG... generated by cleavage of cartilage aggrecan at the site N341-F342.
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申请公布号 |
CA2194352(C) |
申请公布日期 |
2007.01.09 |
申请号 |
CA19952194352 |
申请日期 |
1995.06.30 |
申请人 |
THE UNIVERSITY OF MELBOURNE |
发明人 |
FOSANG, AMANDA JANE |
分类号 |
C12N5/18;G01N33/53;A61K38/00;A61K38/03;A61K38/55;A61K39/395;A61K45/00;A61P29/00;A61P43/00;C07K7/06;C07K16/18;C12N5/10;C12N15/02;C12P21/08;C12Q1/37;C12R1/91 |
主分类号 |
C12N5/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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