BIOSYNTHETIC PROCESS FOR THE PREPARATION OF GALLIDERMIN
摘要
A process for the production of gallidermin comprises fermentative production of the respective biologically in-active and non-toxic pre-form(s) by either genetically engineered producer organism or mutants of the natural producer organism that are deficient for the extracelluar gallidermin pathway specific serine-pro tease. The process includes a downstream process in which a pre-form of gallidermin is isolated from the fermentation and bio-catalytically activated, followed by purification of the mature and active gallidermin.
申请公布号
WO2007000332(A2)
申请公布日期
2007.01.04
申请号
WO2006EP06240
申请日期
2006.06.28
申请人
BIOTECH CONCEPTS GMBH;MINAS, WOLFGANG;PANKE, SVEN;VALSESIA, GIORGIA;MEDAGLIA, GIOVANNI
发明人
MINAS, WOLFGANG;PANKE, SVEN;VALSESIA, GIORGIA;MEDAGLIA, GIOVANNI