ELUCIDATION OF HIGH AFFINITY, HIGH SPECIFICITY OLIGONUCLEOTIDES AND DERIVATIZED OLIGONUCLEOTIDE SEQUENCES FOR TARGET RECOGNITION
摘要
A method is disclosed to obtain oligonucleotide sequences with high affinity to target molecules. By design, the oligonucleotides have a defined primary and secondary structure. The affinity for binding to target species is classified or quantified by assay measurements using physical measurements rather than being based primarily on separations. Targets include but are not limited to proteins, polymers, biological membranes including cells and organelles and small molecules.
申请公布号
WO2006102540(A3)
申请公布日期
2007.01.04
申请号
WO2006US10645
申请日期
2006.03.23
申请人
SYRACUSE UNIVERSITY;HUDSON, BRUCE, S.;BORER, PHILIP, N.