| 发明名称 |
GALK1S AS MODIFIERS OF THE PTEN/AKT PATHWAY AND METHODS OF USE |
| 摘要 |
Human GALKl genes are identified as modulators of the PTEN/AKT pathway, and thus are therapeutic targets for disorders associated with defective PTEN/AK T function. Methods for identifying modulators of PTEN/AKT, comprising screeni ng for agents that modulate the activity of GALKl are provided.
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| 申请公布号 |
CA2612224(A1) |
申请公布日期 |
2007.01.04 |
| 申请号 |
CA20062612224 |
申请日期 |
2006.06.20 |
| 申请人 |
EXELIXIS, INC. |
发明人 |
FRIEDMAN, LORI S.;WARD, KEVIN;BLAKE, ROBERT A.;NIETO-BERGMAN, SUSANA;BRACE, ARTHUR;BJERKE, LYNN MARGARET |
| 分类号 |
A61K39/395 |
主分类号 |
A61K39/395 |
| 代理机构 |
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