The invention provides methods and compositions useful in target sequence suppression, target sequence validation and target sequence down regulation. The invention provides polynucleotide constructs useful for gene silencing or RNA down regulation, as well as cells, plants and seeds comprising the polynucleotides. The invention also provides a method for using microRNA to silence a target sequence or to down regulate RNA.
申请公布号
WO2006044322(A3)
申请公布日期
2007.01.04
申请号
WO2005US36373
申请日期
2005.10.12
申请人
THE ROCKEFELLER UNIVERSITY;TOBODA, JOSE, REYES;ZHANG, XIUREN;SOYANO, TAKASHI;CHUA, NAM-HAI;NIU, QI-WEN;LIN, SHIH-SHUN