发明名称 STABLE PHARMACEUTICAL SOLUTION FORMULATIONS FOR PRESSURIZED METERED DOSE INHALERS
摘要 Aerosol solution formulations for use in an aerosol inhaler which comprise 8-hydroxy-5-[(1R)-1-hydroxy-2-[[(1R)-2-(4-methoxyphenyl)-1- methylethyl]amino] ethyl]-2(1H)-quinolinone or a salt thereof, in particular the hydrochloride salt (TA 2005), as an active ingredient, a propellant containing a hydrofluoroalkane, and a cosolvent, stabilized by addition of a specific small amount of a high concentrated phosphoric acid and optionally by the use of a suitable can having part or all of its internal metallic surfaces lined with an inert organic coating. ® KIPO & WIPO 2007
申请公布号 KR20070000476(A) 申请公布日期 2007.01.02
申请号 KR20067015964 申请日期 2006.08.08
申请人 CHIESI FARMA SPA 发明人 LEWIS DAVID;GANDERTON DAVID;MEAKIN BRIAN;DELCANALE MAURIZIO;PIVETTI FAUSTO
分类号 A61K9/12;A61K9/00;A61K31/4704;A61M15/00;A61P11/06;B65D83/14 主分类号 A61K9/12
代理机构 代理人
主权项
地址