STABILIZED AQUEOUS SUSPENSIONS FOR PARENTERAL USE

摘要

A pharmaceutical aqueous suspension formulation for parenteral administration having substantially stabilized pH, comprising a biologically active steroidal compound, L-methionine in effective concentration for pH controlling and a buffering agent, wherein L-methionine provides production of a pH controlling superadditive effect. The biologically active compound is a steroidal compound, for instance exemestane, medroxyprogesterone acetate and estradiol cypionate or a combination of medroxyprogesterone acetate and estradiol cypionate.