| 摘要 |
The invention describes an isomer, enantiomer, diastereoisomer, or tautomer of a compound, represented by formula (I): wherein: A is O, S, NR, or CR, wherein Ris defined herein; represents either a single or a double bond; Ris selected from: H, halogen, R, OR, SR, COOR, SON(R), N(R), CON(R), NRC(O)Ror NRC(O)NRwherein Rand each Ris defined herein; B is NRor CR, with the proviso that one of A or B is either C Ror CR, wherein Ris defined herein; K is N or CR, wherein Ris defined herein; L is N or CR, wherein Rhas the same definition as Rdefined above; M is N or CR, wherein Rhas the same definition as Rdefined above; Yis O or S; Z is N(R)Ror OR, wherein Ris H or alkyl or NRRwherein Rand Rare defined herein; a salt or a derivative thereof, as an inhibitor of HCV NSpolymerase. |
