发明名称 4-2-(CYCLOALKYLAMINO)PYRIMIDIN-4-YL-(PHENYL)-IMIDAZOLIN-2-ONE DERIVATIVES AS P38 MAP- KINASE INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES
摘要 The present invention is to provide a novel heterocyclic compound of the formula [I]: wherein R1 is a halogen, nitro, an alkyl, etc.; R2 is hydrogen, an alkyl, etc.; Ring A is 2-oxo- 4-imidazolin-3,4-diyl, etc.; Ring B is a cycloalkyl, monocyclic saturated heterocyclic group; X is CH, N; Y is a single bond, CO, SO2; Z is O, NH, etc.; and Ring C is an aryl, a heterocyclic group, or a pharmaceutically acceptable salt thereof, which is useful as a p38 MAP kinase inhibitor.
申请公布号 KR20060135965(A) 申请公布日期 2006.12.29
申请号 KR20067024928 申请日期 2006.11.27
申请人 TANABE SEIYAKU CO., LTD. 发明人 KUBO AKIRA;NAKANE TETSU;NAKAJIMA TATSUO;MURAKAMI TAKANORI;MIYOSHI HIDETAKA;OGASAWARA AKIHITO
分类号 C07D403/14;A61K31/506;C07D401/14;C07D403/04;C07D405/14;C07D409/14;C07D413/14;C07D417/14 主分类号 C07D403/14
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