CYCLIC AMINE DERIVATIVE CONTAINING PPAR REGULATOR

摘要

It is intended to provide a pharmaceutical composition which is excellent as an agent for preventing or treating a disease related to an immunological action such as an autoimmune disease. The pharmaceutical composition comprises one or more members selected from the group consisting of PPAR regulators and one or more members selected from the group consisting of aminoalcohol derivatives having the following general formula (I): (I) (wherein R<SUP>1</SUP> and R<SUP>2</SUP>, which are the same or different, represent a hydrogen atom or the like, R<SUP>3</SUP> represents a C1-C6 alkyl group or a hydroxymethyl group, R<SUP>4</SUP> represents a hydrogen atom, a C1-C6 alkyl group or the like, R<SUP>5</SUP> represents a phenyl group substituted with 1 to 3 groups selected from the group consisting of a hydrogen atom, a halogen atom, a cyano group, a C1-C6 alkyl group and the like, X represents a vinylene group (CH=CH group), an oxygen atom or the like, Y represents a single bond, an oxygen atom or the like, Z represents a single bond, a C1-C8 alkylene group or the like and n represents an integer of 2 or 3) and pharmacologically acceptable salts thereof.