| 发明名称 |
Method of screening for inhibitors of osteopontin |
| 摘要 |
Amino acids 136 to 142 and amino acids 162 to 168 of human osteopontin constitute two sites at which osteopontin interacts with alpha4 integrins. Products capable of disrupting those interactions are useful in therapy, particularly in the treatment of inflammatory diseases.
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| 申请公布号 |
US2006292648(A1) |
申请公布日期 |
2006.12.28 |
| 申请号 |
US20060472730 |
申请日期 |
2006.06.22 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
BARRY SIMON;HORGAN CARMEL;LUDBROOK STEVEN |
| 分类号 |
G01N33/50;G01N33/554;A61K38/00;A61K39/395;A61K39/40;A61K45/00;A61P1/04;A61P3/10;A61P9/10;A61P11/06;A61P19/02;A61P25/00;A61P29/00;A61P31/04;A61P31/06;A61P31/12;A61P35/00;A61P37/02;A61P43/00;C07K7/06;C07K14/52;C07K16/00;C07K16/12;C07K19/00;C12N15/09;G01N33/15;G01N33/68 |
主分类号 |
G01N33/50 |
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