TREATMENT METHOD FOR PREVENTING TRANSPLANTATION TISSUE WITH BIOLOGICAL ORIGIN FROM CALCIFICATION AND TISSUE TREATED THEREBY

摘要

It is intended to provide a tissue for transplantation being free from troubles accompanying transplantation such as calcification. It is also intended to provide a membrane for preventing adhesion by which adhesion caused by a surgical operation or treatment can be prevented. It is found out that when a biocompatible polymer is added to an untreated tissue and then the tissue is exposed to ?-ray irradiation, the tissue is unexpectedly strengthened and calcification is prevented, thereby solving the above problems. Although there has been recognized that decellularization is the key factor in preventing a tissue with a biological origin from calcification, it is indicated that ?-ray irradiation is more efficacious than decellularization. Namely, a membrane for preventing adhesion, by which adhesion can be prevented without inducing troublesome reactions (for example, calcification, an inflammatory reaction, unnecessary cell migration or adhesion, platelet aggregation, acceleration of blood coagulation, etc.), is provided.