METHOD OF PREPARING CLOPIDOGREL AND INTERMEDIATES USED THEREIN
摘要
<p>Optically pure clopidogrel can be prepared in a high yield by optically resolving a racemic form of the compound of formula (II) using an optically active amine to form the optically active form of the compound of formula (III) or its acid-addition salt; and methylating the compound of formula (III) or its acid-addition salt.</p>
申请公布号
WO2006137628(A1)
申请公布日期
2006.12.28
申请号
WO2005KR04017
申请日期
2005.11.28
申请人
HANMI PHARM. CO., LTD.;KIM, EUN SOOK;KIM, HEE CHEOL;KWON, BO SUNG;YUN, SANGMIN;KO, MI YOUNG;KIM, CHEOL KYUNG;SUH, KWEE HYUN
发明人
KIM, EUN SOOK;KIM, HEE CHEOL;KWON, BO SUNG;YUN, SANGMIN;KO, MI YOUNG;KIM, CHEOL KYUNG;SUH, KWEE HYUN