发明名称 |
Novel physiological substance NESFATIN, substance relevant thereto, and use of the substances |
摘要 |
<p>The present invention relates to a novel method of obtaining a factor involved in appetite control and/or body weight control, as well as genes obtained by said method, polypeptides encoded by said genes, or novel polypeptides obtained from the information on polypeptides encoded by said genes as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control. Also the present invention relates to substances that inhibit the effects of said genes or said polypeptides as a means for treating, controlling or diagnosing diseases associated with appetite control and/or body weight control. By using thiazolidine diones having a PPAR³ agonist activity, genes and polypeptides involved in appetite regulation and/or body weight reduction can be obtained. NESFATIN or the like obtained by said method can be used as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control.</p> |
申请公布号 |
AU2006260088(A1) |
申请公布日期 |
2006.12.28 |
申请号 |
AU20060260088 |
申请日期 |
2006.06.23 |
申请人 |
TEIJIN PHARMA LIMITED;NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY |
发明人 |
HIROYUKI SHIMIZU;MASANORI YAMAMOTO;MASATOMO MORI;HIROSHI EGUCHI |
分类号 |
C12N15/00;A01K67/027;A61K38/22;A61K39/395;A61K45/00;A61K48/00;A61P3/04;C07K14/47;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/02;C12Q1/02;C12Q1/68;G01N33/15;G01N33/50 |
主分类号 |
C12N15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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