发明名称 INHIBITION OF ATP-MEDIATED, P2X7 DEPENDENT PATHWAYS BY PYRIDOXAL-5-PHOSPHASTE AND VITAMIN B6 RELATED COMPOUNDS
摘要 <p>P5P can be used as effective treatments for the modulation of P2X7, IL-1ß, and inflammation response, and for diseases in which prevention of P2X7-dependent pathways or prevention of release of IL-1ß is desirable, such as epithelial cancer, leukemia, brain tumors spinal cord injury, tuberculosis, Alzheimer's Disease, neurodegenerative diseases, autosomal recessive polycystic kidney disease, diabetes, including type I diabetes, prostate cancer, and osteoporosis, bone formation and resorption.</p>
申请公布号 WO2006136004(A1) 申请公布日期 2006.12.28
申请号 WO2006CA00717 申请日期 2006.05.05
申请人 MEDICURE INTERNATIONAL INC.;DOUGLAS, DEBORAH 发明人 DOUGLAS, DEBORAH
分类号 A61K31/675 主分类号 A61K31/675
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