发明名称 2-Heteroaryl-imidazotriazinones and their use in the treatment of inflammatory or immune diseases
摘要 The invention relates to 2-Heteroaryl-imidazotriazinones, processes for their preparation and their use in medicaments, esp. for the treatment and/or prophylaxis of inflammatory processes and/or immune diseases. The present invention relates to compounds of the general formula (I) in which R<SUP>1 </SUP>denotes 5- to 10-membered heteroaryl, which is optionally substituted by identical or different residues selected from the group consisting of halogen, (C<SUB>1</SUB>-C<SUB>4</SUB>)-alkyl, trifluoromthyl, cyano, nitro und trifluoromethoxy, denotes 3- to 10-membered carbocyclyl or carbon-bonded, 4- to 10-membered heterocyclyl, whereby carbocyclyl and heterocyclyl are optionally substituted by identical or different residues selected from the group consisting of (C<SUB>1</SUB>-C<SUB>6</SUB>)-aldyl, (C<SUB>1</SUB>-C<SUB>6</SUB>)-aldoxy, hydroxy, halogen, trifluoromethyl and oxo, or denotes (C<SUB>2</SUB>-C<SUB>10</SUB>)-alkyl, which is optionally substituted by identical or different residues selected from the group the group consisting of (C<SUB>1</SUB>-C<SUB>6</SUB>)-alkoxy, hydroxy, halogen, 3- to 10-membered carbocyclyl and oxo.
申请公布号 US2006293326(A1) 申请公布日期 2006.12.28
申请号 US20040480949 申请日期 2004.06.18
申请人 ALONSO-ALIJA CRISTINA;GIELEN HEIKE;HENDRIX MARTIN;NIEWOHNER ULRICH;NIEWOHNER MARIA T;SCHAUSS DAGMAR;BISCHOFF HILMAR;BURKHARDT NILS;GEISS VOLKER;SCHLEMMER KARL-HEINZ;CUTHBERT NIGEL;FITZGERALD MARY F;STURTON GRAHAM 发明人 ALONSO-ALIJA CRISTINA;GIELEN HEIKE;HENDRIX MARTIN;NIEWOHNER ULRICH;NIEWOHNER MARIA T.;SCHAUSS DAGMAR;BISCHOFF HILMAR;BURKHARDT NILS;GEISS VOLKER;SCHLEMMER KARL-HEINZ;CUTHBERT NIGEL;FITZGERALD MARY F.;STURTON GRAHAM
分类号 A61K31/53;A61P1/00;A61P1/04;A61P3/10;A61P7/00;A61P7/04;A61P9/00;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P11/08;A61P13/12;A61P17/00;A61P17/06;A61P19/02;A61P19/08;A61P21/00;A61P25/00;A61P25/24;A61P25/28;A61P27/14;A61P29/00;A61P31/04;A61P31/18;A61P33/06;A61P35/00;A61P37/00;A61P37/02;A61P37/06;A61P37/08;A61P39/00;A61P43/00;C07D401/04;C07D403/04;C07D405/04;C07D409/04;C07D417/04;C07D487/04 主分类号 A61K31/53
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