发明名称 |
Artificial protein, method for absolute quantification of proteins and uses thereof |
摘要 |
The invention provides an artificial protein for quantitative analysis of the proteome of a sample, cell or organism, comprising at least two consecutive peptides linked by a cleavage sequence for separating the peptides; a singular marker on one or more peptide for determination of the absolute amount of this fragment; and N-terminal and C-terminal extensions for protection of the peptides; wherein each peptide represents one single protein of the sample, cell or organism and each peptide is in a defined stoichiometry. The invention further provides a collection of peptides, a vector and a kit comprising the artificial protein and a method for quantitative analysis of the proteome. |
申请公布号 |
EP1736480(A1) |
申请公布日期 |
2006.12.27 |
申请号 |
EP20050090161 |
申请日期 |
2005.06.02 |
申请人 |
ENTELECHON GMBH |
发明人 |
PRATT, JULIE M.;BEYNON, ROBERT;GASKELL, SIMON |
分类号 |
C07K7/08;G01N33/68 |
主分类号 |
C07K7/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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