发明名称 |
STABILIZED 4-AMINO-5-CHLORO-N-[(1R,3r,5S)-8-METHYL-8- AZABICYCLO[3.2.1]OCT-3-YL] -2-[1-METHYLBUT-2-YNYLOXY]-BENZAMIDE CONTAINING COMPOSITION |
摘要 |
The present invention provides stable pharmaceutical compositions containing 4-amino-5-chloro-N-[(1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-2-[1-methylbut-2-ynyloxy]benzamide. Specifically, it provides pharmaceutical compositions containing 1) 4-amino-5-chloro-N-[(1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-2-[1-methylbut-2-ynyloxy]benzamide, a pharmacologically acceptable salt thereof or a hydrate of them; and 2) a basic additive.
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申请公布号 |
EP1736156(A1) |
申请公布日期 |
2006.12.27 |
申请号 |
EP20050734263 |
申请日期 |
2005.04.14 |
申请人 |
EISAI R&D MANAGEMENT CO., LTD. |
发明人 |
NAKATA, HITOSHI;ISHIDA, ATSUNORI |
分类号 |
A61K31/439;A61K9/14;A61K9/16;A61K9/20;A61K9/28;A61K9/48;A61K47/02;A61K47/04;A61K47/12;A61K47/10;A61K47/38;A61P1/00;C07D451/04 |
主分类号 |
A61K31/439 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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