发明名称 |
CHEMOTHERAPY METHOD FOR TREATING MALIGNANT TUMORS IN THE ABDOMINAL CAVITY, SMALL PELVIS AND RETROPERITONEAL SPACE |
摘要 |
FIELD: medicine. ^ SUBSTANCE: method involves introducing water-soluble chemopreparation as a course in lymphotropic way. Riva-Rocci apparatus cuff is applied to lower part of femur and pressure of 40 mm of mercury column is created. 20 ml of chymotrypsin dissolved in 0.5% Novocain solution is subcutaneously introduced into the middle area of lateral shank surface 30 min later. Water-soluble chemopreparations are slowly subcutaneously introduced 0.5 cm below the chymotrypsin injection place in 5-7 min as single dose. The cuff is left in swollen state for 2 h. After having taken off the cuff, 50 ml of 0.5% Novocain solution is subcutaneously introduced into the place of previous water-soluble chemopreparations injection. Then the lower extremity is dressed with elastic bandage. The lymphotropic water-soluble chemopreparations introduction procedure is carried out once a day combined with standard chemotherapy course. Detralex is daily given to the patient on the background of the chemotherapy course at a dose of 2 pills twice a day combined with subcutaneous Fraxiparin injections introduced at a dose of 0.3 ml once a day. ^ EFFECT: avoided surgical intervention; increased antitumor effectiveness; reduced risk of recurrences, metastases and toxic complications. ^ 5 dwg |
申请公布号 |
RU2290184(C1) |
申请公布日期 |
2006.12.27 |
申请号 |
RU20050108770 |
申请日期 |
2005.03.28 |
申请人 |
ROSTOVSKIJ NAUCHNO-ISSLEDOVATEL'SKIJ ONKOLOGICHESKIJ INSTITUT MZ RF;MAKSIMOV GENNADIJ KONSTANTINOVICH;PAVLENKO SERGEJ GEORGIEVICH;IVANOVSKIJ SERGEJ OLEGOVICH;SYCHEVA NATAL'JA LEONIDOVNA;LEONOV ALEKSANDR ALEKSANDROVICH |
发明人 |
MAKSIMOV GENNADIJ KONSTANTINOVICH;PAVLENKO SERGEJ GEORGIEVICH;IVANOVSKIJ SERGEJ OLEGOVICH;SYCHEVA NATAL'JA LEONIDOVNA;LEONOV ALEKSANDR ALEKSANDROVICH |
分类号 |
A61K31/7048;A61K31/245;A61K31/513;A61K31/519;A61K31/727;A61K38/55;A61P35/00 |
主分类号 |
A61K31/7048 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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