发明名称 |
APPARATUS AND METHOD FOR TRANSDERMAL DELIVERY OF MULTIPLE VACCINES |
摘要 |
<p>An apparatus and method for transdermally delivering an immunologically active agent comprising a delivery system having a microprojection array that includes a plurality of microprojections that are adapted to pierce through the stratum corneum into the underlying epidermis layer, or epidermis and dermis layers, the microprojection array having a plurality of array regions, each of the array regions having a different biocompatible coating disposed thereon, wherein at least one of the array region coatings includes an immunologically active agent. In one embodiment, each coating on the array regions includes a different immunologically active agent. In another embodiment, the biocompatible coating on a first array region includes an immunologically active agent and the biocompatible coating on a second array region includes an immune response augmenting adjuvant.</p> |
申请公布号 |
EP1735469(A2) |
申请公布日期 |
2006.12.27 |
申请号 |
EP20050725915 |
申请日期 |
2005.03.18 |
申请人 |
ALZA CORPORATION |
发明人 |
TRAUTMAN, JOSEPH, C.;DADDONA, PETER, E.;CORMIER, MICHEL, J., N. |
分类号 |
C12Q1/70;A61K39/00;A61K39/02;A61K39/12;A61K39/295;A61M31/00;A61M37/00 |
主分类号 |
C12Q1/70 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|