发明名称 2,4-PYRIMIDINEDIAMINES USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES,INFLAMMATORY AND IMMUNE SYSTEM DISORDES
摘要 Novel pyrimidine derivatives of formula (I) and their use for the manufacture of a medicament for the treatment or prevention of a disease which responds to inhibition of FAK and/or ALK and/or ZAP-70 and/or IGF-IR. in which: n' is selected from 1,2 and 3; R' 1 is selected from phenyl, pyridinyl, pyrazolyl and pyrimidinyl; and R' 2 and R' 3 are as described herein.
申请公布号 ZA200600464(B) 申请公布日期 2006.12.27
申请号 ZA20060000464 申请日期 2006.01.17
申请人 NOVARTIS AG 发明人 GARCIA-ECHEVERRIA CARLOS;KAWAHARA EIJI;MATSUURA NAOKO;OHMORI OSAMU;STEENSMA RUO;JIANG JIQING;DING QIANG;GRAY NATHANAEL SCHIANDER;KANAZAWA TAKANORI;MASUYA KEILCHI;MIYAKE TAKAHIRO;UMEMURA ICHIRO;CHOPIUK GREG;WAN YONGQIN;ZHANG QIONG;KARANEWSKY DONALD
分类号 A61K;A61P;A61P29/00;A61P37/00;C07D;C07D239/48;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D405/14;C07D498/04 主分类号 A61K
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