发明名称 |
2,4-PYRIMIDINEDIAMINES USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES,INFLAMMATORY AND IMMUNE SYSTEM DISORDES |
摘要 |
Novel pyrimidine derivatives of formula (I) and their use for the manufacture of a medicament for the treatment or prevention of a disease which responds to inhibition of FAK and/or ALK and/or ZAP-70 and/or IGF-IR.
in which: n' is selected from 1,2 and 3;
R' 1 is selected from phenyl, pyridinyl, pyrazolyl and pyrimidinyl;
and R' 2 and R' 3 are as described herein. |
申请公布号 |
ZA200600464(B) |
申请公布日期 |
2006.12.27 |
申请号 |
ZA20060000464 |
申请日期 |
2006.01.17 |
申请人 |
NOVARTIS AG |
发明人 |
GARCIA-ECHEVERRIA CARLOS;KAWAHARA EIJI;MATSUURA NAOKO;OHMORI OSAMU;STEENSMA RUO;JIANG JIQING;DING QIANG;GRAY NATHANAEL SCHIANDER;KANAZAWA TAKANORI;MASUYA KEILCHI;MIYAKE TAKAHIRO;UMEMURA ICHIRO;CHOPIUK GREG;WAN YONGQIN;ZHANG QIONG;KARANEWSKY DONALD |
分类号 |
A61K;A61P;A61P29/00;A61P37/00;C07D;C07D239/48;C07D401/12;C07D401/14;C07D403/12;C07D405/12;C07D405/14;C07D498/04 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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