发明名称 DIAZA-SPIROPIPERIDINE DERIVATIVES
摘要 The present invention relates to compounds of formula (I); wherein A-B is -CH2-CH2-, - CH2-O- or -O-CH2-; X is hydrogen or hydroxy; Rl is aryl, optionally substituted by one or two substituents, selected from the group consisting of halogen, lower alkyl, cyano, CF3, - OCF3, lower alkoxy, -SO2-lower alkyl or by heteroaryl, R2 is aryl, optionally substituted by one or two substituents, selected from the group consisting of halogen, lower alkyl, CF3 or lower alkoxy; R3 is hydrogen or lower alkyl; n is 0, 1 or 2; and to their pharmaceutically active salts. The compounds of formula I may be used in the treatment of neurological and neuropsychiatric disorders.
申请公布号 KR20060133546(A) 申请公布日期 2006.12.26
申请号 KR20067013641 申请日期 2006.07.06
申请人 F. HOFFMANN-LA ROCHE AG 发明人 CECCARELLI SIMONA MARIA;JOLIDON SYNESE;PINARD EMMANUEL;THOMAS ANDREW WILLIAM
分类号 C07D471/10;A61K31/407 主分类号 C07D471/10
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