发明名称 [4-(5-AMINOMETHYL-2-FLUORO-PHENYL)-PIPERIDIN-1-YL]-(4-BROMO-3-METHYL-5-PROPOXY-THIOPEN-2-YL)-METHANONE HYDROCHLORIDE AS AN INHIBITOR OF MAST CELL TRYPTASE
摘要 The present invention extends to the compound of formula I, or a prodrug, pharmaceutically acceptable salt, or solvate of said compound. Furthermore, the present invention is directed to a pharmaceutical composition comprising a pharmaceutically effective amount of the compound of formula I, and a pharmaceutically acceptable carrier. Furthermore, the present invention is directed to the use of a compound of formula I as an inhibitor of tryptase, comprising introducing the compound into a composition comprising tryptase. In addition, the present invention is directed to the use of a compound of formula I for treating a patient suffering from, or subject to, a physiological condition in need of amelioration of an inhibitor of tryptase comprising administering to the patient a therapeutically effective amount of the compound of Claim 1. The present invention is directed also to the preparation of a compound of formula I.
申请公布号 KR20060130682(A) 申请公布日期 2006.12.19
申请号 KR20067019886 申请日期 2006.09.26
申请人 AVENTIS PHARMACEUTICALS, INC. 发明人 GAO ZHONGLI;DAVIS LARRY;LEVELL JULIAN;CZEKAJ MARK;SLEDESKI ADAM W.;HADDAD EL BDAOUI
分类号 C07D409/06 主分类号 C07D409/06
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