| 发明名称 |
Pyrazolo[1,5-a]pyridine derivatives and their use as neurotransmitter modulators |
| 摘要 |
The present invention relates to novel pyrazolo[1,5-a]pyridine derivatives of general formula I: that bind with high affifnity to CRF<SUB>1 </SUB>receptors, including human CRF<SUB>1 </SUB>receptors. This invention also relates to methods of using the compounds of the invention to treat a disorder or condition, the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as CNS disorders or diseases, particularly anxiety disorders, and depression and stress related disorders.
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| 申请公布号 |
US7151109(B2) |
申请公布日期 |
2006.12.19 |
| 申请号 |
US20030387159 |
申请日期 |
2003.03.12 |
| 申请人 |
PHARMACIA & UPJOHN COMPANY LLC |
发明人 |
FU JIAN-MIN |
| 分类号 |
A61K31/44;A61K31/415;A61K31/437;A61K31/444;A61P1/04;A61P3/04;A61P3/10;A61P5/14;A61P9/10;A61P11/06;A61P15/08;A61P17/06;A61P19/10;A61P21/00;A61P21/04;A61P25/00;A61P25/06;A61P25/08;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P25/32;A61P25/34;A61P25/36;A61P29/00;A61P31/18;A61P35/00;A61P37/00;A61P37/06;A61P37/08;A61P43/00;C07D471/04 |
主分类号 |
A61K31/44 |
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