发明名称 Propenecarboxylic acid amidoxime derivatives, a process for the preparation thereof, and pharmaceutical compositions containing the same
摘要 The invention refers to novel propenecarboxylic acid amidoxime derivatives furthermore N-oxides and/or geometrical isomers and/or optical isomers and/or pharmaceutically suitable acid addition salts and/or quaternary derivatives thereof. The novel compounds are suitable for the treatment of a state connected with oxygen deficit and/or energy deficit, or a disease based on PARP inhibition, especially an autoimmune or neurodegenerative disease, and/or a viral disease, and/or a disease caused by a toxic effect.
申请公布号 US7151175(B2) 申请公布日期 2006.12.19
申请号 US20050084231 申请日期 2005.03.21
申请人 N-GENE RESEARCH LABORATORIES INC. 发明人 LITERATI NAGY PETER;SUMEGI BALAZS;TAKACS KALMAN
分类号 C07D295/12;C07D403/00;A61K31/155;A61K31/16;A61K31/40;A61K31/4245;A61K31/4453;A61K31/454;A61K31/4725;A61K31/495;A61K31/496;A61K31/535;A61K31/5375;A61K31/5377;A61K31/5395;A61K31/55;A61P1/04;A61P1/16;A61P3/04;A61P3/10;A61P7/02;A61P9/00;A61P9/02;A61P9/10;A61P9/12;A61P17/00;A61P17/02;A61P17/06;A61P19/02;A61P21/04;A61P25/00;A61P25/02;A61P25/16;A61P25/28;A61P29/00;A61P31/04;A61P31/14;A61P31/18;A61P37/02;A61P43/00;C07C249/06;C07C251/40;C07D207/325;C07D215/38;C07D217/00;C07D271/06;C07D271/07;C07D273/02;C07D273/04;C07D295/13;C07D413/00;C07D413/06 主分类号 C07D295/12
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