发明名称 [3,4-a:3,4-c]carbazole compounds
摘要 A compound selected from those of formula (I): wherein: W<SUB>1 </SUB>represents, together with carbon to which it is bonded, phenyl, pyridyl, Z represents a group of formula U-V as defined in the description, Q<SUB>1 </SUB>represents oxygen, NR<SUB>2 </SUB>as defined in the description, Q<SUB>2 </SUB>represents oxygen, NR'<SUB>2 </SUB>as defined in the description, X<SUB>1</SUB>, X<SUB>2</SUB>, X'<SUB>1 </SUB>and X'<SUB>2 </SUB>each represents hydrogen, hydroxy, alkoxy, mercapto or alkylthio, Y<SUB>1</SUB>, Y<SUB>2</SUB>, Y'<SUB>1 </SUB>and Y'<SUB>2 </SUB>each represents hydrogen, or X<SUB>1 </SUB>and Y<SUB>1</SUB>, X<SUB>2 </SUB>and Y<SUB>2</SUB>, X'<SUB>1 </SUB>and Y'<SUB>1</SUB>, X'<SUB>2 </SUB>and Y'<SUB>2 </SUB>with carbon carrying them, together form carbonyl or thiocarbonyl, R<SUB>1 </SUB>is as defined in the description, its isomers, and addition salts thereof with a pharmaceutically acceptable acid or base, and medicinal products containing the same which are useful in the treatment of cancer.
申请公布号 US7151108(B2) 申请公布日期 2006.12.19
申请号 US20030672418 申请日期 2003.09.26
申请人 LES LABORATORIES SERVIER 发明人 PRUDHOMME MICHELLE;HUGON BERNADETTE;ANIZON FABRICE;HICKMAN JOHN;PIERRE ALAIN;GOLSTEYN ROY;RENARD PIERRE;PFEIFFER BRUNO
分类号 A61K31/437;A61K31/40;A61K31/403;A61K31/407;A61K31/7056;A61K31/706;A61P35/00;A61P43/00;C07D471/22;C07D487/14;C07D491/14;C07D491/147;C07H19/23 主分类号 A61K31/437
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