| 摘要 |
A method of deuteration in which a compound with aromatic ring and/or heterocycle having an enhanced deuteration ratio can be obtained. There is provided a method of deuterating a compound with aromatic ring and/or heterocycle, characterized in that a compound with aromatic ring and/or heterocycle is reacted with a deuterium source in the presence of an activated mixed catalyst composed of at least two members selected from among a palladium catalyst, a platinum catalyst, a rhodium catalyst, an iridium catalyst, a ruthenium catalyst, a nickel catalyst and a cobalt catalyst.
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