发明名称 FLUORO SUBSTITUTED CYCLOALKANOINDOLES AND THEIR USE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS
摘要 Fluoro substituted cycloalkanoindole derivatives of formula (I) and pharmaceutically acceptable salts thereof, wherein n is 0 or 1; m is 1, 2 or 3; R1 is H, C1-C3 alkyl, halogenated C1-C3 alkyl or cyclopropyl; R2 is 4-chlorophenyl or 2,4,6-trichlorophenyl are antagonists of prostaglandins, and as such are useful for the treatment of prostaglandin mediated diseases.
申请公布号 RS62404(A) 申请公布日期 2006.12.15
申请号 YU2004P000624 申请日期 2003.01.22
申请人 MERCK FROSST CANADA LTD 发明人 BERTHELETTE CARL;LACHANCE NICOLAS;LI LIANHAI;STURINO CLAUDIO;WANG ZHAOYIN
分类号 A61K45/00;A61K31/404;A61P11/06;A61P27/16;A61P37/08;A61P43/00;C07D209/00;C07D209/80;C07D209/88;C07D209/94;(IPC1-7):C07D209/80;A61K31/403 主分类号 A61K45/00
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