发明名称 PHENYLETHENYL OR PHENYLETHINYL DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS
摘要 This invention relates to the use of compounds of formula (I) wherein R1, R2, R3, R4 and R5 are as defined in the description, A signifies -CH=CH- or -C=C-; and B signifies (B1); (B2); (B3); (B4); (B5) or (B6); wherein R6 to R26, X and Y have the significances given in the description, as well as pharmaceutically acceptable salts thereof, for the manufacture of medicaments for the treatment or prevention of mGluR5 receptor mediated disorders.
申请公布号 RS43903(A) 申请公布日期 2006.12.15
申请号 YU2003P000439 申请日期 2001.11.26
申请人 F.HOFFMANN-LA ROCHE AG 发明人 MUTEL VINCENT;PETERS JENS-UWE;WICHMANN JUERGEN
分类号 C07D233/64;A61K31/4045;A61K31/415;A61K31/4164;A61K31/4174;A61K31/4178;A61K31/4245;A61K31/437;A61K31/4985;A61P1/08;A61P9/02;A61P9/10;A61P13/02;A61P21/02;A61P25/00;A61P25/04;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/34;A61P25/36;A61P31/18;A61P43/00;C07D209/14;C07D209/16;C07D231/12;C07D233/54;C07D233/58;C07D233/68;C07D233/90;C07D233/92;C07D233/94;C07D403/06;C07D403/10;C07D413/04;C07D491/147;C07D495/14;C07D498/04;C07D513/14;(IPC1-7):C07D233/90;A61K31/416 主分类号 C07D233/64
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