发明名称 |
POLYAMIDNUKLEINSÄURE-DERIVATE, MITTEL UND VERFAHREN ZUR IHRER HERSTELLUNG |
摘要 |
The present invention relates to PNA derivatives which carry, at the C terminus, or at both the C and N termini of the PNA backbone, one or more phosphoryl radicals. The phosphoryl radicals carry, where appropriate, one or more labeling groups, groups for crosslinking, groups which promote intracellular uptake, or groups which increase the binding affinity of the PNA derivative for nucleic acids. The invention furthermore relates to a process for preparing the above-mentioned PNA derivatives and to their use as pharmaceuticals or diagnostic agents. |
申请公布号 |
DE50111371(D1) |
申请公布日期 |
2006.12.14 |
申请号 |
DE2001511371 |
申请日期 |
2001.04.07 |
申请人 |
SANOFI-AVENTIS DEUTSCHLAND GMBH |
发明人 |
UHLMANN, EUGEN;BREIPOHL, GERHARD;WILL, WILLIAM |
分类号 |
C07K14/00;G01N33/53;A61K38/00;A61K48/00;A61P11/06;A61P17/00;A61P17/06;A61P31/16;A61P31/18;A61P35/00;C07F9/40;C08G69/48;C12Q1/04;C12Q1/68;G01N21/78;G01N33/566;G01N33/58 |
主分类号 |
C07K14/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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