发明名称 |
Administration of a thiol-based chemoprotectant compound |
摘要 |
A method of administration of a thiol-based chemoprotectant agent including NAC (N-acetylcysteine) and STS (sodium thiosulfate) that markedly affects biodistribution and protects against injury from diagnostic or therapeutic intra-arterial procedures. A method for treating or mitigating the side effects of cytotoxic cancer therapy for tumors located in the head or neck and brain tumors. The thiol-based chemoprotectant agent is administered intra-arterially with rapid and first pass uptake in organs and tissues other than the liver. |
申请公布号 |
AU2001253919(B2) |
申请公布日期 |
2006.12.14 |
申请号 |
AU20010253919 |
申请日期 |
2001.04.26 |
申请人 |
OREGON HEALTH SCIENCES UNIVERSITY;GOVERNMENT OF THE UNITED STATES, D/B/A DEPARTMENTOF VETERANS AFFAIRS |
发明人 |
LESLIE MULDOON;EDWARD A. NEUWELT;MICHAEL A. PAGEL |
分类号 |
A61K9/08;A61K31/095;A61K31/195;A61K31/198;A61K31/337;A61K31/661;A61K33/04;A61K33/24;A61K38/05;A61K38/06;A61K45/00;A61K47/06;A61P35/00;A61P43/00 |
主分类号 |
A61K9/08 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|