发明名称 |
REGULATOR OF ALDOSTERONE RECEPTOR |
摘要 |
<p>Disclosed is a compound represented by the general formula (1) or a prodrug thereof or a pharmaceutically acceptable salt of the compound or prodrug which has a prophylactic or therapeutic effect on various diseases such as hypertension, stroke and heart failure. (1) wherein A represents the following formula (A-1) or the like: (A-1) where R<SUP>1</SUP> represents a hydrogen atom or the like; R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP> and R<SUP>5</SUP> independently represent a hydrogen atom, an alkyl group which may be substituted or the like; Z<SUP>1</SUP>, Z<SUP>2</SUP>, Z<SUP>3</SUP> and Z<SUP>4</SUP> independently represent a nitrogen atom or CR<SUP>6</SUP>; R<SUP>6</SUP> independently represents a hydrogen atom or the like; X represents an oxygen atom or the like; Y represents an oxygen atom or the like; L represents a single bond or the like; and B represents an aryl group which may be substituted, a heteroaryl group which may be substituted or the like.</p> |
申请公布号 |
WO2006132295(A1) |
申请公布日期 |
2006.12.14 |
申请号 |
WO2006JP311479 |
申请日期 |
2006.06.08 |
申请人 |
DAINIPPON SUMITOMO PHARMA CO., LTD.;KATAYAMA, SEIJI;SUDA, HITOSHI |
发明人 |
KATAYAMA, SEIJI;SUDA, HITOSHI |
分类号 |
A61P29/00;C07D409/12;C07D413/12;C07D413/14;C07D417/12;C07D417/14;C07F7/18;C07D267/06;A61K31/553;A61P5/40;A61P5/42;A61P7/10;A61P9/00;A61P9/04;A61P9/06;A61P9/10;A61P9/12;A61P13/12 |
主分类号 |
A61P29/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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