发明名称 |
GLP-1 ANALOGUE FORMULATIONS |
摘要 |
<p>The present invention relates to compositions forming a low viscosity mixture of: a) at least one neutral diacyl lipid, such as a diacyl glycerol; b) at least one phospholipid, such as a phosphatidyl choline; c) at least one biotolerable solvent, such as an oxygen containing solvent; d) at least one GLP-1 analogue; wherein the pre-formulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with an aqueous fluid. The invention further relates to methods of treatment comprising administration of such compositions, especially in treating diabetes, and to pre-filled administration devices and kits containing the formulations.</p> |
申请公布号 |
WO2006131730(A1) |
申请公布日期 |
2006.12.14 |
申请号 |
WO2006GB02079 |
申请日期 |
2006.06.06 |
申请人 |
CAMURUS AB;GODDARD, CHRISTOPHER;JOABSSON, FREDRIK;JOHNSSON, MARKUS;TIBERG, FREDRIK |
发明人 |
JOABSSON, FREDRIK;JOHNSSON, MARKUS;TIBERG, FREDRIK |
分类号 |
A61K9/10;A61K9/06;A61K9/12;A61K38/26 |
主分类号 |
A61K9/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|