摘要 |
<p>An oral care composition, comprising: a therapeutically effective amount of a compound having the structure of Formula [I]; or a salt thereof to produce a cooling sensation, wherein R<SUP>1</SUP> and R<SUP>2</SUP> are independently selected from hydrogen or halogen atoms; hydroxy, cyano, nitro, mercapto, carbonyl, sulfone and carboxy groups; or optionally substituted alkyl, alkenyl, alkoxy, alkylthio, aryl, aryloxy, arylthio, amino, siloxy, ester and heterocyclic groups, characterized by an oil soluble agent for solubilising or emulsifying the cooling compound.</p> |