| 摘要 |
The present invention is related to pharmaceutical compositions comprising prostanoid-receptor agonists, intravaginal dosage forms comprising the same, and methods of making and using the same. The present invention is also related to a controlled release pharmaceutical gel for vaginal administration, the pharmaceutical gel comprising: (a) misoprostol; (b) a cellulose derivative; and (c) a polyol; wherein the gel is a substantially nonaqueous gel, and wherein the gel forms a hydrogel when placed in a vaginal tract.
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