| 发明名称 |
SULFONAMIDE DERIVATIVES USEFUL AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTl) INHIBITORS |
| 摘要 |
<p>The invention is concerned with novel sulfonamide derivatives of Formula (I); wherein R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, A, X, Y<SUP>1</SUP>, Y<SUP>2</SUP>, Y<SUP>3</SUP>, Y<SUP>4</SUP> and Z<SUP>1</SUP> are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds inhibit L-CPT1 and can be used as medicaments.</p> |
| 申请公布号 |
WO2006131452(A1) |
申请公布日期 |
2006.12.14 |
| 申请号 |
WO2006EP62652 |
申请日期 |
2006.05.29 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG;BLEICHER, KONRAD;CECCARELLI, SIMONA MARIA;CHOMIENNE, ODILE;MATTEI, PATRIZIO;SCHULZ-GASCH, TANJA;STAHL, CHRISTOPH MARTIN |
发明人 |
BLEICHER, KONRAD;CECCARELLI, SIMONA MARIA;CHOMIENNE, ODILE;MATTEI, PATRIZIO;SCHULZ-GASCH, TANJA;STAHL, CHRISTOPH MARTIN |
| 分类号 |
C07C311/21;A61K31/196;A61K31/42;A61K31/505;A61P3/10;C07C311/29;C07D409/04;C07D413/04 |
主分类号 |
C07C311/21 |
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