发明名称 |
METHOD OF STABILIZING MACROLIDE COMPOUND |
摘要 |
A method of stabilizing a macrolide compound and a process for efficiently producing the compound. The method, which is for stabilizing a 12-membered cyclic macrolide compound, e.g., that represented by the formula (I), comprises causing the compound to coexist with a cyclodextrin. The process, which is for producing the macrolide compound, comprises causing a cyclodextrin to be present in a culture medium containing an actinomyces having the ability to produce the macrolide compound.
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申请公布号 |
KR20060127946(A) |
申请公布日期 |
2006.12.13 |
申请号 |
KR20067015399 |
申请日期 |
2006.07.28 |
申请人 |
EISAI R&D MANAGEMENT CO., LTD.;MERCIAN CORPORATION |
发明人 |
ISHIHARA HIROSHI;TAKEDA SUSUMU;YAMADA TOMONARI;ASAHI YOSHIAKI |
分类号 |
C07D407/06;C07D313/00;C08B37/16;C12N1/20;C12P17/08;C12P17/16 |
主分类号 |
C07D407/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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