发明名称 |
ABCA1 STABILIZER |
摘要 |
<p>To provide a pharmaceutically effective prophylactic/preventive agent for low-HDL cholesterolemia, focusing on an HDL-generating mechanism. The ABCA1 stabilizer of the present invention contains a bisphenol-type compound selected form probucol spiroquinone, probucol diphenoquinone, and probucol bisphenol as an effective ingredient. The ABCA1 stabilizer can continuously and stably express ABCA1 by a mechanism quite different from that of conventional processes, and thus is useful as prophylactic/preventive agent for low-HDL cholesterolemia or arteriosclerosis.</p> |
申请公布号 |
EP1704857(A8) |
申请公布日期 |
2006.12.13 |
申请号 |
EP20040808067 |
申请日期 |
2004.12.22 |
申请人 |
ASKA PHARMACEUTICAL CO., LTD. |
发明人 |
YOKOYAMA, SHINJI;TSUJITA, MAKI;ARAKAWA, REIJIRO;AOTSUKA, TOMOJI |
分类号 |
A61K31/05;A61K31/122;A61K31/385;A61P3/04;A61P3/06;A61P9/10;A61P43/00 |
主分类号 |
A61K31/05 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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