发明名称 Indoles as NAALADase inhibitors
摘要 This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALAdase levels are altered, effecting neuronal activity, effecting TGF-beta activity, inhibiting angiogenesis, and treating glutamate abnormalities, neuropathy, pain, compulsive disorders, prostate diseases, cancers and glaucoma.
申请公布号 US7148250(B2) 申请公布日期 2006.12.12
申请号 US20040500319 申请日期 2004.11.22
申请人 GUILFORD PHARMACEUTICALS INC. 发明人 TSUKAMOTO TAKASHI;GRELLA BRIAN;MAJER PAVEL
分类号 A61K31/404;A61K31/405;A61P43/00;C07D209/02;C07D209/34;C07D209/42 主分类号 A61K31/404
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