发明名称 PROCESS FOR THE PREPARATION OF SUBSTITUTED THIAZOLIDINEDIONE
摘要 A process for preparing a compound of formula (I) or a tautomeric form there of or a pharmaceutically acceptable salt thereof or a pharmaceutically acceptable solvate thereof, wherein: J represents O or S; T represents a substituted or unsubstituted aryl group and T1 is O or S; which process comprises reducing a compound of formula (II) or a tautomeric form thereof or a salt thereof or a solvate thereof, wherein T and T1 are as defined in relation to formula (I), with a complex hydride reducing agent or a source of a complex hydride reducing agent; and thereafter, as required, preparing a pharmaceutically acceptable salt or a pharmaceutically acceptable solvate of the compound of formula (I) or a tautomeric form thereof.
申请公布号 CA2281695(C) 申请公布日期 2006.12.12
申请号 CA19982281695 申请日期 1998.02.13
申请人 SMITHKLINE BEECHAM P.L.C. 发明人 MOORE, STEPHEN;LEWIS, NORMAN JOHN;URQUHART, MICHAEL;POOL, COLIN RIPLEY;QUICK, JOHN KIRBY;GILES, ROBERT GORDON
分类号 C07D277/20;C07D277/34;C07D;C07D263/36;C07D263/44;C07D277/36;C07D413/12;C07D413/14;C07D417/06;C07D417/10;C07D417/12;C07D417/14 主分类号 C07D277/20
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