发明名称 METHOD OF TREATING PATIENTS WITH OPERABLE MAMMARY GLAND CANCER
摘要 FIELD: oncology. ^ SUBSTANCE: treatment consists in performing 2-4 courses of preoperative chemotherapy with 2-weak intervals between courses, each course comprising intravenous administration of methotrexate in dose 40 mg/m2 on first or eighth day and intramuscular cyclophosphanin dose 100 mg/m2 during 14 days, while introducing additionally oral Xeloda in dose 1000 mg/m2 twice a day on the first to fourteenth days. ^ EFFECT: achieved complete regression of tumor focus owing to high selectivity of Xeloda preparation diminishing toxic effect of chemotherapy. ^ 3 ex
申请公布号 RU2288710(C2) 申请公布日期 2006.12.10
申请号 RU20040129377 申请日期 2004.10.05
申请人 GOSUDARSTVENNOE UCHREZHDENIE NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT ONKOLOGII TOMSKOGO NAUCHNOGO TSENTRA SIBIRSKOGO OTDELENIJA ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK GU NII ONKOLOGII TNTS SO RAMN 发明人 SLONIMSKAJA ELENA MIKHAJLOVNA;KRASULINA NATAL'JA ANATOL'EVNA;DOROSHENKO ARTEM VASIL'EVICH;KOKORINA JULIJA LEONIDOVNA;GARBUKOV EVGENIJ JUR'EVICH
分类号 A61K31/196;A61K31/513;A61K31/675;A61P35/00 主分类号 A61K31/196
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