发明名称 USING COMPOUND COMBINING PROPERTY OF SEROTONIN REVERSE UPTAKE INHIBITOR AND AGONIST OF 5-HT1A-RECEPTOR
摘要 FIELD: organic chemistry, veterinary science. ^ SUBSTANCE: invention relates ton using a compound combining properties of inhibitor of serotonin (5-HT) reverse uptake and agonist of 5-HT1A-receptors as an agent used in treatment of disorders associated with behavior stressors in veterinary medicine. Indicated compound is chosen from the group consisting of 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoylbenzofuran-5-yl)-piperazine or its physiologically acceptable salt or 3-{4-[4-(4-cyanophenyl)-piperazin-1-yl]-butyl}-1H-indole-5-carbonitrile or its physiologically acceptable salt. Invention provides higher level of inhibition of indicated disorders in animals as compared with the known analogues. ^ EFFECT: improved and valuable medicinal and veterinary properties of compound. ^ 4 cl, 3 ex
申请公布号 RU2288719(C2) 申请公布日期 2006.12.10
申请号 RU20030115431 申请日期 2001.10.16
申请人 MERK PATENT GMBKH 发明人 GERD BARTOSHIK
分类号 A61K31/495;C07D405/12;A61K31/496;A61K45/06;A61P25/18;A61P25/22;C07D209/14 主分类号 A61K31/495
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