发明名称 Conditionally replicating viruses and methods for cancer virotherapy
摘要 The present invention provides for methods and compositions for translation of a viral vector both in vitro and in vivo. Specifically, the present invention pertains to a translational control element placed in a vector to cause a selective translation of a viral vector. In one embodiment, the present invention provides for methods and compositions for conditionally expressing a viral vector inside tumor cells, while leaving normal cells unaffected due to their inability to translate the vector
申请公布号 US2006275262(A1) 申请公布日期 2006.12.07
申请号 US20050261525 申请日期 2005.10.28
申请人 发明人 MATHIS JAMES M.;DEBENEDETTI ARRIGO;CURIEL DAVID T.
分类号 A61K48/00;C12N15/861 主分类号 A61K48/00
代理机构 代理人
主权项
地址