摘要 |
Discrete samples ( 13, 13 a) are introducedinto a mixing chamber containing a carrier fluid (5), so that the samples ( 13, 13 a) move from an inlet ( 4 ) to an outlet ( 7 ) of the mixing chamber. One or more reagents ( 12, 12 a, 14, 14 a) are also introduced into the mixing chamber, which move from the inlet ( 4 ) to contact and mix with the corresponding samples ( 13, 13 a) at a location ( 15 ) in the mixing chamber, to form respective processed samples ( 16, 16 a, 16 b, 16 c) for further processing or analysis. The location of contact ( 15 ) is predetermined by predetermining the rate of movement of the samples ( 13, 13 a) and of each reagent ( 12, 12 a, 14, 14 a). The method and apparatus permit rapid automated processing, are suitable for very small sample and reagent volumes (eg, 100 nanolitres), and minimize contamination.
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