| 发明名称 |
ANTIVIRAL BIFUNCTIONAL MOLECULES, METHODS OF CONSTRUCTION AND METHODS OF TREATING VIRUS-INDUCED CANCER THEREWITH |
| 摘要 |
The present invention relates to molecules that are capable of killing cells. The molecules comprise: a targeting agent and a channel-forming moiety. The molecules may be polypeptides. The present invention also relates to polynucleotide sequences encoding the polypeptides of the invention. In a preferred embodiment, the channel-forming moiety comprises a colicin and the targeting agent is an antibody. Methods of treatment by administering the molecules of the present invention are also provided. |
| 申请公布号 |
WO2006103494(A3) |
申请公布日期 |
2006.12.07 |
| 申请号 |
WO2005IB04155 |
申请日期 |
2005.12.09 |
| 申请人 |
WEST CHINA HOSPITAL, SICHUAN UNIVERSITY;QIU, XIAO-QING |
发明人 |
QIU, XIAO-QING |
| 分类号 |
C07K14/435;A61K38/16;A61K38/17;A61K47/48;A61P31/12;A61P35/00;C07K14/195;C07K14/245;C07K16/08;C12N15/09;C12N15/12;C12N15/13;C12N15/31;C12N15/62;C12N15/63;C12N15/64;C12N15/85;C12P21/02 |
主分类号 |
C07K14/435 |
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